Thursday, September 15
Preliminary Program – Day 1
12:00 Registration and Welcome Coffee
12:30 Welcome Notes and Introduction
Karin Hartmann (Basel, Switzerland)
12:40 Status of the ECNM in 2022 and Future Perspectives
Peter Valent (Vienna, Austria) & Massimo Triggiani (Salerno, Italy)
12:50 Presentation of the Researcher of the Year 2022
Massimo Triggiani (Salerno, Italy) & Peter Valent (Vienna, Austria)
12:55 Lecture of the Researcher of the Year 2022
Development of Diagnostic Criteria and a Classification of MCAS
Cem Akin (Ann Arbor, MI, USA)
13:25 Coffee Break
13:40 Session I: Diagnostic Workup and Prognostication in Systemic Mastocytosis
Chairs: Tracy George (Salt Lake City, UT, USA) & Michael Doubek (Brno, Czech Republic)
13:40 Standards of Pathology in the Diagnosis of SM and Updated WHO Criteria
Karl Sotlar (Salzburg, Austria)
14:00 Histologic Response Assessment in Advanced SM
Tracy George (Salt Lake City, UT, USA)
14:20 Special Challenges in Pathologic Workup and Grading of SM
Hans-Peter Horny (Munich, Germany)
14:40 Pathologic Features of Extramedullary Organ Involvement in SM
Alexandar Tzankov (Basel, Switzerland)
15:00 Coffee Break
15:15 Session II: Molecular Characterization in Mastocytosis
Chairs: Alberto Orfao (Salamanca, Spain) & Michel Arock (Paris, France)
15:15 Standards of Genetic Testing in the Diagnosis and Prognostication of SM
Gregor Hoermann (Munich, Germany)
15:35 Updated Consensus on KIT Mutation Analysis in Mastocytosis: Application to Diagnosis, Prognosis and Follow-Up
Michel Arock (Paris, France)
15:55 Acquired Genetic Variants and Their Prognostic Impact in SM
Ivan Alvarez-Twose (Toledo, Spain)
16:15 Keynote Lecture: Role of Dynamin-Related Protein 1 in Mast Cell Activation
Stephen J. Galli (Stanford, CA, USA)
16:45 Coffee Break
17:00 Session III: Mast Cell Activation Syndromes and Hereditary Alpha-Tryptasemia
Chairs: Mariana Castells (Boston, MA, USA) & Dean D. Metcalfe (Bethesda, MD, USA)
17:00 Classification and Prognostication of MCAS in 2022
Peter Valent (Vienna, Austria)
17:20 Baseline and Transiently Increased Tryptase in ISM and HT
Lawrence B. Schwartz (Richmond, VA, USA)
17:40 Tryptase Genotyping in Mast Cell Disorders: Diagnostic Implications and Clinical Presentation
Jon Lyons (Bethesda, MD, USA)
18:00 Clinical Characteristics in Subjects with HT: A Critical Data Review
Cem Akin (Ann Arbor, MI, USA)
18:20 Summary of DAY 1 and Announcements
Karin Hartmann (Basel, Switzerland) & Peter Valent (Vienna, Austria)
18:30 Dinner